Highly efficient suicide gene expression in hepatocellular carcinoma cells by Epstein-Barr virus-based plasmid vectors combined with polyamidoamine dendrimer
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منابع مشابه
Evaluation of Changes in NFKB Gene Expression Following Epstein-Barr Virus and its Participation in the Half-Life of Patients With Acute Epstein-Barr Positive Lymphoblastic Leukemia
Aim: Leukemia targets are one of the most common childhood malignancies. Epstein-Barr virus is a tumorigenic virus of the herpes family of viruses and causes primary infection in young children. The aim of this study was to evaluate the increase in NFKB expression following EBV virus and its contribution to the half-life of EBV-positive acute lymphoblastic leukemia patients. Materials and Meth...
متن کاملCombination of Epstein-Barr Virus-Based Plasmid and Nonviral Polymeric Vectors for Enhanced and Prolonged Gene Expression
Department of Biochemistry, College of Natural Sciences, Chungnam National University, Daejeon 305-764, Korea Graduate School of Analytical Science and Technology, Chungnam National University, Daejeon 305-764, Korea *E-mail: [email protected] School of Chemistry and Molecular Engineering, Seoul National University, Seoul 151-742, Korea *E-mail: [email protected] Received July 17, 2012, ...
متن کاملTHE IN VITRO GROWTH PROPERTIES OF CELL LINES FROM EPSTEIN-BARR VIRUS-INDUCED TAMARIN TUMORS AND TAMARIN B CELLS TR ANSFORMED BY EPSTEIN BARR VIRUS
EBV-carrying human cell lines, depending on whether the cells are derived from Burkitt's lymphoma (BL) tumor biopsies or transformed by EBV in vitro, have different growth properties in vitro. In contrast, there are no clear differences between tamarin tumor lines and tamarin LCLs in vitro. Both types of tamarin cell lines could grow in agarose and formed colonies unlike human LCLs, althoug...
متن کاملEpstein-barr virus-positive gastric carcinoma has a distinct protein expression profile in comparison with epstein-barr virus-negative carcinoma.
PURPOSE EBV has been detected in 2-16% of gastric carcinomas. However, there is little information available about the gene expression profile of EBV-positive gastric carcinomas. EXPERIMENTAL DESIGN EBV infection was examined using EBV-encoded small RNAs (EBERs) in situ hybridization, and 63 (5.6%) of 1127 consecutive gastric carcinomas were found to be EBV-positive. The expressions of 27 tum...
متن کاملMolecular Characterization of the Epstein-Barr Virus BGLF2 Gene, its Expression, and Subcellular Localization
Background: Epstein–Barr virus (EBV) is a universal herpes virus which can cause a life-long and largely asymptomatic infection in the human population. However, the exact pathogenesis of the EBV infection is not well known.Objective: A comprehensive bioinformatics prediction was carried out for investigating the molecular properties of the BGLF2 and to a...
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ژورنال
عنوان ژورنال: Cancer Gene Therapy
سال: 2000
ISSN: 0929-1903,1476-5500
DOI: 10.1038/sj.cgt.7700079